AP3B2 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molec µLes. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Immunogen : adaptor-related protein complex 3, beta 2 subunit
Aliases : AP 3 complex subunit beta 2, AP3B2, Beta 3B adaptin, DKFZp686D17136, NAPTB
Observed MW : 120-140 kDa
Uniprot ID : Q13367
Reactivity : Human, Mouse, Rat
Application : ELISA, WB,IP
Recommended dilution : WB : 1 : 200-1 : 2000 IP : 1 : 200-1 : 2000
Gene ID : 8120
Research Area : Signal Transduction, Metabolism