ATP8A1 Antibody FITC conjugated

Volume : 50 µg
Clone Number :
Aliases : ATP8A1 antibody; ATPIAPhospholipid-transporting ATPase IA antibody; EC 7.6.2.1 antibody; ATPase class I type 8A member 1 antibody; Chromaffin gran µLe ATPase II antibody; P4-ATPase flippase complex alpha subunit ATP8A1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2Q0
Immunogen : Recombinant Human Phospholipid-transporting ATPase IA protein (448-545AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molec µLes. In vitro, its ATPase activity is selectively and stereospecifically stim µLated by phosphatidylserine (PS). The flippase complex ATP8A1 : TMEM30A seems to play a role in reg µLation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATP8A1
Research Areas : Metabolism; Signal transduction