ARHGEF5 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : ARHG5_HUMAN antibody; ARHGEF 5 antibody; ARHGEF5 antibody; DKFZp686N1969 antibody; ephexin 3 antibody; Ephexin-3 antibody; GEF 5 antibody; GEF5 antibody; Guanine nucleotide reg µLatory protein TIM antibody; Oncogene TIM antibody; P60 antibody; p60 TIM antibody; Rho guanine nucleotide exchange factor (GEF) 5 antibody; Rho guanine nucleotide exchange factor 5 antibody; TIM 1 antibody; TIM antibody; TIM1 antibody; Transforming immortalized mammary oncogene antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q12774
Immunogen : Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide exchange factor which activates Rho GTPases (PubMed : 15601624). Strongly activates RHOA (PubMed : 15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in reg µLation of cell shape and actin cytoskeletal organization (PubMed : 15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed : 14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive reg µLation of immature dendritic cell migration (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ARHGEF5
Research Areas : Signal transduction