ANLN Antibody

Volume : 50 µL
Clone Number :
Aliases : Actin binding protein scraps homolog Drosophila antibody; Actin binding protein anillin antibody; Actin-binding protein anillin antibody; Anillin actin binding protein antibody; anln antibody; ANLN_HUMAN antibody; DKFZp779A055 antibody; FSGS8 antibody; Scra antibody; Scraps antibody; Scraps homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQW6
Immunogen : Fusion protein of Human ANLN
Raised in : Rabbit
Species Reactivity : Human, Mouse
Tested Applications : ELISA, IHC; ELISA : 1 : 1000-1 : 2000, IHC : 1 : 25-1 : 100
Background : Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen affinity purification
Conj µgate : Non-conj µgated
Buffer : -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ANLN
Research Areas : Cell biology;Signal transduction