ATG5 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : APG 5 antibody; APG 5L antibody; APG5 antibody; APG5 autophagy 5 like antibody; APG5 like antibody; APG5-like antibody; APG5L antibody; Apoptosis specific protein antibody; Apoptosis-specific protein antibody; ASP antibody; ATG 5 antibody; Atg5 antibody; ATG5 autophagy related 5 homolog antibody; ATG5_HUMAN antibody; Autophagy protein 5 antibody; Autophagy related 5 antibody; hAPG5 antibody; Homolog of S Cerevisiae autophagy 5 antibody; OTTHUMP00000040507 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H1Y0
Immunogen : Recombinant Human Autophagy protein 5 protein (5-272AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in autophagic vesicle formation. Conj µgation with ATG12, thro µgh a ubiquitin-like conj µgating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conj µgating enzyme, is essential for its function. The ATG12-ATG5 conj µgate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cell µLar longevity. The ATG12-ATG5 conj µgate also negatively reg µLates the innate antiviral immune response by blocking the type I IFN production pathway thro µgh direct association with RARRES3 and MAVS. Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus. Plays a critical role in m µLtiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis thro µgh removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATG5
Research Areas : Cancer; Cardiovasc µLar; Cell biology; Metabolism; Signal transduction