ANGPT2 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : AGPT 2 antibody; Agpt2 antibody; ANG 2 antibody; ANG-2 antibody; ANG2 antibody; Angiopoietin 2a antibody; Angiopoietin 2B antibody; Angiopoietin-2 antibody; Angiopoietin2 antibody; ANGP2_HUMAN antibody; ANGPT 2 antibody; Angpt2 antibody; Tie2 ligand antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15123
Immunogen : Recombinant Human Angiopoietin-2 protein (19-485AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds to TEK/TIE2, competing for the ANGPT1 binding site, and mod µLating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vasc µLar regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ANGPT2
Research Areas : Cardiovasc µLar