Initially, Warfarin was introduced as a rat and mice killer. It was the most effective poison until other, more potent pesticides were brought about. A few years after, Warfarin was found to be an effective anticoagulant. It can help prevent embolism and thrombosis, both of which are bleeding disorders that come with several health conditions. It was in 1950s that Warfarin was finally approved for use in the medical world.
Warfarin prevents blood clots from forming abnormally in the blood vessels. It is used for patients with heart problems, risks for thrombosis, and pulmonary embolism. It belongs to the class of drug that is also known as blood thinners.
Warfarin comes in tablet form. It is usually prescribed to be taken by mouth once daily. Warfarin can be taken with or without meals.
Usually, a Warfarin treatment is started on a low dose and is just adjusted as you go along depending on the results of your blood tests. Yes, therapy for this drug requires regular blood check-up to keep a close watch on how you are reacting to the drug. For the most part, Warfarin is prescribed to be used for a period of time, until your risks for thrombosis and embolism pass. Make sure that you continue taking your medicine unless your doctor tells you otherwise.
Warfarin is a complex drug that must be taken carefully, under close supervision of a doctor. If it is not handled properly, it may pose serious and even fatal threats. Warfarin may cause bleeding disorders to go on overdrive. That is why it is highly important that you discuss with your doctor all the possible factors that may affect or interact with your drug treatment.
First thing to be established is your possible allergic reactions with Warfarin. Then, tell your doctor about your medical history including your bouts with several health conditions such as blood problems, hypertension, heart conditions, cancer, aneurysm, anemia, and kidney or liver ailments. Those who went under surgery or a serious injury recently are also not advised to take Warfarin.
Older people aged 65 and beyond must take Warfarin with extra precautions. Bleeding profusely is most likely to happen in older patients. Bleeding also comes naturally when you are just starting with the treatment.
To be safe with Warfarin, therefore, your doctor needs to single out each and every factor that may worsen your risk for bleeding. That also includes the drugs that you are currently taking, your physical activities, and your genetic make-up.
Warfarin causes several other side effects apart from possible risks for bleeding. The mild ones include stomach upset, tiredness, hair loss, and chills. You must talk to your doctor if you feel your symptoms are getting worse or are persistent. The common side effects of Warfarin usually go away after a few days. Also, you must call your doctor immediately once you experience less common but serious symptoms of side effects. Allergic reactions, hoarseness, chest pains, fever, severe nausea and vomiting, appetite loss, joint and muscle pains, and numbness are causes for serious alarms.
Warfarin has the following structural formula:
• Molecular formula of warfarin is C19H16O4
• Chemical IUPAC Name is 2-hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-4-one
• Molecular weight is 308.328 g/mol
• Warfarin available : 1mg tablets, 2mg tablets, 2.5mg tablets, 3mg tablets, 4mg tablets, 5mg tablets, 6mg tablets, 7.5mg tablets, 10mg tablets
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Review published on: 28 April 2009
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