Tranexamic acid is often given to patients suffering from excessive bleeding. This medication is an antifibrinolytic that completely slows down the creation of plasminogen to plasmin, which is a molecule that can cause the degradation of fibrin. Fibrin is the basic framework for blood clot formation during hemostasis. It has about eight times the antifibrinolytic activity of its predecessor drugs.
Take this drug orally, usually two to four times a day or as prescribed by your healthcare specialist. The length of treatment and dosage of tranexamic acid is based on your response to treatment and your current medical condition. Your weight may also affect your dosage.
Do not increase your dose by yourself, take it more frequently, or take it for a longer time than prescribed. Consult your doctor for any dosage adjustments. To get the most benefit out of this medication, simply take it regularly and don't miss a dose. To help you remember taking it, take it at the same time daily.
Before you take tranexamic acid, inform your doctor your medical history, which may include allergies, eye problems, retina or color vision issues, history of blood clots or bleeding, subarachnoid hemorrhage or any other type of head injury, and kidney disease.
Notify your doctor of all the prescription or nonprescription drugs you've used or you're currently using, especially if it's aspirin or other NSAIDs like ibuprofen, aminocaproic acid, anticoagulants or blood thinners like heparin or warfarin, anti-inhibitor coagulant concentrates, factor IX complex, or blood-clot-inducing medications like birth control pills or estrogen supplements.
Also of note is the fact that many nonprescription products contain NSAIDs, so it will be prudent for you to check prescription labels carefully and consult your pharmacist in regards to this issue. The kidneys remove this medication, so the elderly may be more sensitive to the effects of this drug because kidney function declines as you get older.
You should also report to your doctor if you are or plan to be pregnant before taking this drug. Breastfeeding should be avoided as well because this medication passes into human milk. Talk with your doctor before attempting to breastfeed while under tranexamic acid treatment.
Tranexamic acid can make you dizzy, so use caution while using heavy machinery, driving, or doing anything that requires alertness while under treatment. Remember to not start or stop taking this drug without doctor or pharmacist consent. Limit your alcohol intake as well, because it can worsen the drowsiness side effect of the drug.
You should take note that your doctor has probably prescribed this drug to you because he or she has deemed its benefits as greater than the risks for side effects and complications. Many people under tranexamic acid treatment do not suffer from any serious side effects.
Diarrhea, nausea, and vomiting are the most common side effects of this drug. If any of these symptoms continue or become more severe, notify your healthcare specialist immediately. Vision changes and dizziness are more unlikely symptoms, but you must report these to your doctor promptly if they ever occur. Finally, if you notice any other side effects not listed above, contact your doctor or pharmacist as well.
Tranexamic acid has the following structural formula:
• Molecular formula of tranexamic acid is C8H15NO2
• Chemical IUPAC Name is 4-(aminomethyl)cyclohexane-1-carboxylic acid
Brand name(s): Amcha, Amikapron, Amstat, Anvitoff, Carxamin, Cyclocapron, Cyklokapron, Emorhalt, Frenolyse, Mastop, Rikavarin, Rikavarin-S, Tamcha, Tranexan, Transamin, Trasamlon, Ugurol
Review published on: 03 April 2009
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