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Reboxetine review
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An antidepressant drug, Reboxetine is used as treatment for clinical depression, Attention Deficit Hyperactivity Disorder (ADHD), Attention Deficit Disorder (ADD), panic disorder, and other social phobias. Manufactured by Pfizer, Reboxetine also helps patients maintain and sustain the improvements that they are making.
Due to problems with negative interaction, some medicines cannot be taken simultaneously with Reboxetine. This includes Monoamine oxidase (MAO) inhibitors. MAO inhibitors are another form of antidepressants. Hence, Reboxetince cannot be taken with other anti-depressants as well as other forms of medicines that alter mood.
Although it rarely occurs, Reboxetine does have the tendency to increase the risk of seizures. As such, patients with history of convulsive disorders must be monitored closely.
Reboxetine can also cause hypotension, a condition in which the blood pressure decreases significantly. Consequently, Reboxetine may magnify the effects of anti-hypertensive drugs. If the patient is already taking a certain drug to control and lower his blood pressure, the doctor should be careful about prescribing also Reboxetine. IN such a case, the patient must be under close supervision in order to help his blood pressure in check.
Reboxetine is also an advisable mode of treatment for patients who have glaucoma as well as problems with urine retention.
As for pregnant women, there is not enough data to confirm Reboxetine’s effect on the fetus. Reboxetine can still be taken as long as the doctor decides that the situation of the patient is grave and must be addressed immediately.
However, it must also be remembered Reboxetine does not work instantly. Even though the treatment may have started, some patients may still have suicidal tendencies. This can eventually be resolved as the treatment progresses.
Generally, the effect of Reboxetine will be observed 14 days after the first treatment.
Reboxetine is available in tablet form which is taken orally. In adults, the treatment starts with 4 mg per day. If there is no noticeable response from the patient, the doctor can increase the dosage to 10 mg. However, the increase can only be made 3 weeks after the first dose.
For the elderly and for those with liver or kidney problems, the recommended dose is 2 mg per day. Eventually, this can be increased to 6 mg.
About 70% of patients experience the side effects of Reboxetine. This includes dry mouth, insomnia and constipation. Some also experience motion sickness or vertigo. Urinary retention is also a common case. Excessive sweating is also a possible side effect.
In more severe cases, Reboxetine can cause impotence. This usually happens to patients who receive more than 8mg of Reboxetine per day.
Heart palpitations are also a common occurrence. Low blood pressure is also a major concern so there is a need for close patient supervision.
Sexual dysfunctions may also occur. Taking Reboxetine can decrease a person’s sex drive as well as his ability to reach orgasm.
If side effects are felt, the patient must report to the doctor. While the side effects are temporary, the doctor can modify the dosage to make you feel more comfortable.
Reboxetine has the following structural formula:
• Molecular formula of reboxetine is C19H23NO3
• Chemical IUPAC Name is (2S)-2-[(S)-(2-ethoxyphenoxy)-phenylmethyl]morpholine
• Molecular weight is 313.3908 g/mol
• Reboxetine available : 2mg tablets and 4mg tablets
Brand name(s): Davedax, Edronax, Norebox, Prolift, Solvex, Vestra
Review published on: 23 March 2009
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