Miconazole is a kind of antifungal drug. This medication prevents the growth of fungus on the skin.
Miconazole is prescribed to individuals who have various skin infections like ringworm, athlete’s foot, tinea versiculor, jock itch, and yeast infections. It is known under various brand names like Aloe Vesta, Baza, Desenex, Cruex, Fungoid, Micatin, Mitrazol, Ony-Clear, and Monistat Derm.
Miconazole is applied topically. Patients should first clean then dry the area before applying this medication. The drug can be applied 1-2 times a day and this should last for 2-4 weeks.
For vaginal candidiasis, the usual dosage for adult is insertion of 1200 mg suppository done at bedtime for a one-day therapy. For a week-long therapy, the dosage is at 100 mg of suppository administered intravaginally. For a 3-day therapy, the dosage is 200 mg administered intravaginally during bedtime.
Patients should use miconazole as prescribed by the doctor or physician. Miconazole should be used for the full schedule prescribed by the doctor even if the patient feels better. There is a risk that the symptoms may come back before an infection has been fully healed. In case the infection does not improve after 4 weeks or it even gets worse, patients should immediately consult their doctors.
Patients should also avoid using bandages since it will not allow air to circulate over the area. Instead, use of gauze made of light cotton may be tapped as protective clothing.
This medication should be stored at room temperature and kept away from direct heat and moisture.
Patients may experience side effects from the use of miconazole, although most of the time these side effects occur during the first few days of treatment even as the body adjusts to the medication. However patients should also be wary of serious side effects and immediately seek medical help in case any of the symptoms appear.
Some of these serious side effects include difficulty in breathing, sore throat, swelling of the face, lips, and tongue, or hives.
Some of the less serious side effects that patients may experience include itching, burning and irritation of the skin, and frequent urination.
Patients should talk to their doctors or pharmacists in case any of these side effects continue or worsen.
Patients should avoid wearing clothes that are tight-fitting or those made of synthetic materials such as panty hose because these clothes do not allow air to circulate inside the affected area. It is advisable that patients instead use loose-fitting items made of natural fibers like cotton until the infection has been fully healed.
Miconazole should not be applied in the eyes, mouth, or nose. Patients should tell their doctors their medical history before taking this medication. They should also be open about the other medications they are taking like warfarin or Coumadin. Doctors may have to monitor the patient or adjust the dosage in case the patient takes the abovementioned medication. It is also not advised to use other types of vaginal creams with miconazole unless prescribed by a doctor.
Miconazole has the following structural formula:
• Molecular formula of miconazole is C18H14Cl4N2O
• Chemical IUPAC Name is 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
• Molecular weight is 416.127 g/mol
• Miconazole available : 2% cream
Brand name(s): Benzoylmetronildazole, Daktarin, Femizol-M, Micatin, Miconazole Nitrate, Micozole, Minostate, Monistat, Zeasorb-AF
Review published on: 11 September 2009
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