Metolazone is a diuretic or water pill which increases urination and helps the body to remove excess water. It is effective in the treatment of high blood pressure and its related complications.
Metolazone is prescribed to individuals who have high blood pressure. It can prevent complications such as strokes, kidney problems, and heart attacks. It can also reduce the swelling and fluid retention resulting from conditions like kidney disease and congestive heart failure. It can also help improve conditions like difficulty in breathing.
This medication is marketed under the brand name Zaroxolyn.
This medication is administered orally even on an empty stomach. Dosage is usually once a day. However it is usual for doctors to vary the dosing of this medication to conform to the condition and the response to the treatment of the patient. It is recommended that this medication is taken early, at least before 6 in the evening, to avoid instances wherein the patient has to wake up to urinate at night. It is advised that patients follow their dosing schedule to get the most benefit from thie medication. It is also advised that they take this drug the same time every day so they will not forget it. This drug should be taken even if the patient feels better . It can take up to 6 weeks before a patient sees lower blood pressure as a result of using this medication.
Patients may suffer from less serious side effects of this medication such as dizziness, headache, lightheadedness, vision problems, upset stomach, loss of appetite, diarrhea and constipation. Most of the time, these side effects happen as the body adjusts to the use of metolazone. In case any of these effects continue, patients should immediately seek medical help.
There is also the risk that this medication can result to excessive loss of water and minerals in the body. This is characterized by symptoms like muscle cramps, severe dizziness, confusion, unusual drying of the mouth, nausea or vomiting, irregular heartbeat, infrequent urination, seizures, and fainting. It is unlikely that metolazone can result to serious allergic reaction, although patients are advised to seek medical help immediately if they experience itching, rashes, swelling, difficulty in breathing, and severe dizziness.
Patients are discouraged from drinking alcohol since it can increase some side effects of this medication. Patients should also avoid taking other medicines which can make them light-headed such as drugs for narcotic pain, seizures, and muscle cramps. These medications may aggravate the side effects of metolazone. Patients should also avoid becoming dehydrated by drinking the right amount of liquids. However, drinking too much liquid can also be harmful.
Some of the medications that can interact with this medication are lithium, digoxin, steroids, insulin, methenamine, blood thinners like warfarin, salicylates like aspirin, furosemide, and non-steroidal anti-inflammatory drugs like aspirin, diclofenac, ibuprofen, naproxen, indomethacin, and piroxicam.
Patients who have severe liver disease or those who have difficulties in urinating should also not take this medication.
Metolazone has the following structural formula:
• Molecular formula of metolazone is C16H16ClN3O3S
• Chemical IUPAC Name is 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
• Molecular weight is 365.835 g/mol
• Metolazone available : 0.5mg tablets
Brand name(s): Diulo, Metalazone, Metalozone, Metenix, Metolazona, Metolazonum, Microx, Mykrox, Oldren, Xuret, Zaroxolyn
Review published on: 10 September 2009
 Your Metolazone review
Other popular drugs: Chlorpropamide ::
Infliximab ::
Chloroquine
|
Home
E-Mail
Site Map
http://www.medical-look.com
FORUM 
Buy Metolazone
