Mefenamic Acid falls under the classification of a group of medications known as NSAIDs, or nonsteroidal anti-inflammatory drugs. It works by reducing inflammation and providing short-term relief from pain.
Mefenamic Acid is prescribed for the treatment of mild to moderately severe pains, like headaches, menstrual cramps, toothaches, muscle pain, rheumatism, athletic injuries, sprains, lower back pain, pain stemming from minor surgery like tooth extraction, and tendinitis.
Mefenamic Acid is also used as an antipyretic drug to lower body temperatures, such as in cases of fever.
Patients who are on this medication are advised from taking over-the-counter drugs for alleviating colds or allergies, including other pain medications such as aspirin, ibuprofen or naproxen. These medications have a similar composition as Mefenamic Acid and the patient may end up taking too much of the same type of drug.
Mefenamic Acid should not be taken with alcohol, as alcohol increases the possibility of the patient suffering from stomach bleeding. Patients who have liver disorders should inform their doctor of their condition so as to be prescribed with a lower dose of this NSAID. Likewise, patients suffering from kidney ailments or renal conditions should avoid Mefenamic Acid entirely, as it can accumulate within their excretory system and cause complications.
Patients who are allergic to NSAIDs like aspirin, those with blood disorders, ulcers, heart conditions, high blood pressure, asthma, or eye diseases should inform their doctor before taking Mefenamic Acid. This medication can also cause drowsiness, so performing activities which require a high level of alertness should be avoided while taking this medication.
Mefenamic Acid makes the skin more susceptible to sunlight; patients are therefore advised not to use sunlamps, and to avoid staying under the sun for long periods of time. If this is unavoidable, they should apply sunscreen and wear protective clothing whenever they are outdoors. Patients who are pregnant or breastfeeding should consult their doctor before beginning treatment to discuss whether the benefits of taking Mefenamic Acid far outweigh the risks it can pose to the unborn child or breastfeeding infant.
Long-term use of Mefenamic Acid can increase the risks of a person acquiring heart or circulatory disorders, heart attack or stroke. Patients should inform their doctor if they smoke, or if they have a personal or family history of heart disease, myocardial infarction (heart attack), stroke, high cholesterol and high blood pressure, or diabetes. Patients who are about to undergo, or have just undergone a coronary bypass procedure should avoid this medication at all costs.
Mefenamic Acid also increases the chances of stomach or intestine bleeding, or perforations, and patients should call their doctor immediately if they exhibit symptoms like black, tarry or bloody stools, and bloody vomit that resembles coffee grounds.
Patients should inform their doctor of any other over-the-counter or prescription medications, or vitamin, mineral and herbal supplements they are taking so as to rule out any drug which might have an adverse reaction when taken with Mefenamic Acid.
The side effects of Mefenamic Acid include nausea, vomiting, diarrhea, anorexia, heartburn, gastroenteritis, stomach pains, ulcers, headaches, flatulence, drowsiness and dizziness, nervousness, fatigue, anxiety, sleep difficulties like insomnia, and blurry vision.
It is distributed in capsule form under the brand names Ponstel, Ponstan and Dolfenal. Mefenamic acid is most effective when taken as soon as pain is felt. And since it can cause an upset stomach, it should be taken with food or milk every 6 hours for up to one week, but never for more than 7 days at a time.
Mefenamic acid has the following structural formula:
• Molecular formula of mefenamic acid is C15H15NO2
• Chemical IUPAC Name is 2-(2,3-dimethylphenyl)aminobenzoic acid
• Molecular weight is 241.285 g/mol
• Mefenamic acid available : 250mg tablets, 500mg tablets
Generic name: Mefenamic Acid
Brand name(s): Acide Mefenamique, Bafameritin-M, Bafhameritin-M, Bonabol, Coslan, Lysalgo, Mefacit, Mefanamic Acid, Mefenacid, Mefenaminsaeure, Mephenamic Acid, Mephenaminic Acid, Methenamic Acid, Namphen, Parkemed, Ponalar, Ponstan, Ponstel, Ponstil, Ponstyl, Pontal, Tamany Bonsan, Tanston, Vialidon
Review published on: 24 June 2008
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