Lipinox is a calcium channel blocker used mainly for chest pain, often referred to as angina, and hypertension. Calcium makes the arteries contract and become narrow, Lipinox helps the blood flow into the heart more smoothly by blocking the calcium. It relaxes the muscles in the arteries to help the heart pump blood, it reduces blood pressure and increases blood flow to other parts of the body. Chest pain is greatly reduced by the extra supply of blood to the heart. Usually the medicament of choice when treating hypertension and angina, Lipinox helps the heart manage hypertension by increasing the blood flow and relaxing the muscles, so the heart doesn't have to work so hard.
Any prescription or non-prescription medicaments must be discussed with your healthcare professional before taking Lipinox. Prescription medicaments for HIV, AIDS, prostate problems, seizures, fungal infections, bacterial infections, or diuretics may result in a negative interaction if taken with Lipinox. Even herbal medicaments, natural supplements, large amounts of calcium, or vitamins can alter the effectiveness of the medicament.
In the event that the patient has had liver or heart disease those organs may be weakened and thus more susceptible to the harmful Lipinox effects. Inform your healthcare professional immediately if you have ever had any of these illnesses.
Patients already taking nitroglycerin for angina may continue taking it. Nitroglycerin can be taken with Lipinox without any harmful effects.
Some known side effects include: edema, dizziness, headache, upset stomach, rashes, drowsiness, arrhythmia, skin edema of the hands and feet, and excessive tiredness. These are negligible side effects that are common with most medicaments. Patients must be careful not to drive after taken Lipinox because of the drowsiness that comes with taking the medicament. More serious side effects include severe chest pain, irregular heartbeat and fainting. If any of these occur seek immediate medical attention.
It is not known if Lipinox is harmful to pregnant women; however, if you are pregnant or become pregnant during treatment, inform your healthcare professional as a precaution. Only take Lipinox if the benefits outweigh the potential danger to the fetus. A warning to mothers: researchers have not confirmed if the medicament is passed through breast milk, so nursing mothers should stop breastfeeding while on Lipinox.
Lipinox is commonly distributed under the names Norvasc and Istin. It is usually available in 5-10 mg tablets. Healthcare professionals typically prescribe 5mg at the beginning of treatment then gradually increase the dose as they see fit. Lipinox usually is in effect for a full 24 hours, so the dose is typically daily. When using this medicament, a low-sodium diet will help the medicament with its course of action.
Lipinox has the following structural formula:
• Molecular formula of lipinox is C20H25ClN2O5
• Chemical IUPAC Name is methylethyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6- methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Molecular weight is 408.876 g/mol
• Lipinox available : 2.5mg tablets, 5mg tablets, 10mg tablets
Generic name: Amlodipine
Brand name(s): Amlocard, Amlodipino, Amlodipinum, Amlodis, Amvaz, Coroval, Lotrel, Norvasc
Review published on: 19 January 2010
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