Imurek, an immunosuppressant used to weaken the immune system, also goes by the brand names Imurek and Azasan. This medication is available in pill form, as an injection, or intravenously. Imurek is administered to patients anticipating an organ transplant or who have already been given a new organ, to help prevent rejection by the immune system. This medication is also given to reduce the signs and symptoms of rheumatoid arthritis. Imurek is also used to treat ulcerative colitis. Other inflammatory conditions can be treated by Imurek. These include systemic lupus erythematosus, inflammatory myositisis, inflammatory bowel illness, and vasculitis. The condition usually improves in six to eight weeks, though it can sometimes take up to twelve weeks.
Imurek's most important side effect to note is that it can cause a decrease in the number of blood cells in your bone marrow. Contact your physician immediately if you experience any unusual bleeding or bruising, fatigue, headache, confusion or dizziness, increased heart rate, weakness, difficulty breathing, sore throat, pyrexia, chills, or any signs of infection. This medication can increase your risk of developing some cancers, like skin cancer and lymphoma. Inform your physician if you have ever taken any cancer medicaments or if you find any suspicious lumps or masses on your body.
Common side effects include an upset stomach, vomiting or diarrhoea, muscle soreness, blurred vision, mouth sores, coughing, lack of energy or appetite, flu-like symptoms, rash, or yellowing of the skin or eyes. Consult your physician if these symptoms are severe or persist. While taking Imurek, have regular blood tests done to ensure that these side effects are not inhibiting your treatment. Some patients are not able to take Imurek, or may require a lower dose or special monitoring during treatment.
If you are pregnant or may become pregnant, discuss the benefits and risks of this medication with your physician. Studies on the effects of Imurek offer contradicting conclusions with respects to the safety of this medication for pregnant women. Early studies indicated that Imurek would not cause any deformities or issues for a developing fetus, and very little risk for pregnant women or their babies. However, recent studies suggest that harm to the fetus can result from taking Imurek. No conclusions have been reached regarding how much harm or what levels of medication put a fetus in danger. It is always best to err on the side of caution. Due to the uncertainty surrounding this, exercise extreme caution if you are pregnant and considering treatment with Imurek. Do not breastfeed while taking this medication. It is a cytotoxic medication and can be harmful to nursing babies.
Imurek has the following structural formula:
• Molecular formula of imurek is C9H7N7O2S
• Chemical IUPAC Name is 6-(3-methyl-5-nitro-imidazol-4-yl)sulfanyl-7H-purine
• Molecular weight is 277.264 g/mol
• Imurek available : 50mg tablets
Generic name: Azathioprine
Brand name(s): Azamun, Azanin, Azasan, Azathioprin, Azatioprin, Azothioprine, Ccucol, Imuran, Imurel, Muran, Rorasul
Review published on: 02 April 2010
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