Evra is a contraceptive medication that is administered as a patch on the skin. It consists of three layers and works on a four week cycle, in which you apply a new patch once a week for three weeks, and then do not wear a patch at all for the fourth week. The new patch should be changed on the same day of the week, and only one patch should be worn at a time.
If you are starting Evra for the first time, you should wait until the day you begin your period, then you can choose whether you want to begin on that day, or if you want to choose the “Sunday start” option and begin on the Sunday following the first day of your period. The patch should go on clean, dry, healthy skin on your buttock, stomach, upper torso or upper arm, in a p lace where it won’t be rubbed or peeled off by your clothing. You should not put it on your breasts.
You should be careful that your patch is fully stuck to your skin at all times. If it comes even partially detached, you may not be receiving the full amount of medication you need and you may not be fully protected against pregnancy. If your patch comes off before your seven days are up, put another patch on immediately. If you forget to change your patch on your regular patch change day, change it immediately as soon as you remember. If you have let it go for more than two days, you may not be fully protected from pregnancy, and you should begin a new 4-week cycle immediately.
Some common side effects of Evra can include breast tenderness or swelling, headache, skin irritation at the site of the patch, nausea, upper respiratory infection, menstrual cramps, breakthrough bleeding or spotting, change in menstrual flow including heavy periods, swelling, migraine, allergic rash, depression, yeast infection and abdominal cramps. Other side effects can include vomiting, moodiness, weight loss or gain, changes in the eyes, dizziness, excessive hair growth or hair loss, acne, colitis, changes in libido and the inability to conceive for a period of time after discontinuing the medication. Some side effects are rare but serious, and can include blood clots, heart attack, brain hemorrhage, high blood pressure, gallbladder disease, or benign liver tumors.
Evra is in Pregnancy Category X, which means that you must not continue to wear the patch if you discover that you are pregnant. It can lead to harm to a developing fetus. Evra passes into breast milk and has been known to have adverse effects on a nursing child, so women who receive treatment with Evra should not breast feed their child, or she should not use Evra until her child is weaned. Girls who have not yet begun to menstruate should not use the Evra patch, but it is considered to be as safe for adolescent girls as for adults.
Evra has the following structural formula:
• Molecular weight is 327.47 + 296.41
• Evra available : 150-20mcg/24hr patches |
Review published on: 26 March 2008
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