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  Etoricoxib

 


Etoricoxib

Etoricoxib review by Medicalook.com




Etoricoxib is a type of medicine popularly known as a non-steroidal anti-inflammatory drug or NSAID. How do NSAIDs work? They block the action or effect of cyclo-oxygenase, a certain substance found in the human body which is involved in producing prostaglandins. Prostaglandins are responsible for the pain, inflammation and swelling when there are injuries or certain diseases. Since NSAIDs block the action of cyclo-oxygenase that produce prostaglandins in the body, they are effective in relieving pain and reducing inflammation in the body.

Etoricoxib is considered to belong to a ne generation of NSAIDs. They effectively block the action of cyclo-oxygenase type 2 substances (COX-2). Etoricoxib inhibits the production of inflammatory prostaglandins without affecting the production of the prostaglandins that protect the intestines and stomach. Etoricoxib is more popular than other types of NSAIDs because unlike traditional NSAIDs, it succesfuuly reduces inflammation and pain but does not cause harmful side effects to the intestine and stomach of the person taking the medicine.

Most doctored prescribe Etoricoxib to patients who are suffering from acute gout, osteoarthritis and inflammatory disease of the joints. If you can notice, the abovementioned diseases give patients painful episodes. The aim of the doctor in prescribing Etoricoxib to patients who are suffering from the abovementioned diseases is to alleviate the pain and discomfort that comes along with inflammation.

If you are prone to fatigue and dizziness, you should tell your doctor about it because Etoricoxib may alter one’s ability to successfully drive a car or operate mechanical stuffs because it tends to reduce the physical and/or mental ability of a person.

You should also inform your doctor if you have a dysfunctional or impaired heart, kidney(s) or liver so that your health will be closely monitored while you are on medication. If you have a medical history of experiencing decreased liver function, decreased kidney function, high blood pressure, dehydration, liver cirrhosis, heart disease, or heart failure, you should inform your doctor immediately so that your medication can be managed and monitored properly.

If you have experienced having ulceration, bleeding or perforation in your stomach or intestines, you should not take Etoricoxib immediately. Consult your doctor first because you might endanger your health more if you are not particular with your medicine intake. People who are also above 65 years of age should check with their doctor first before they take Etoricoxib.

Etoricoxib may be an effective drug and has minimal side effects compared to other NSAIDs but it is still always a good thing to be careful in taking medicines.

You should not use Etoricoxib if you have suffered or is suffering from the following: bleeding in the intestines or stomach, active peptic ulcer, inflammatory bowel disease related to Crohn’s disease or ulcerative colitis, decreased kidney function, asthma, rhinitis, angiodema, nasal polyps, and urticaria.

Pregnant women, children under 16 years of age and breastfeeding women should not take Etoricoxib because it may cause unpleasant effects in their body. If you have a history of being allergic to certain drug ingredients, it is best for you to look at the ingredients of Etoricoxib prior to intake so that you will not encounter any aversive experience with Etoricoxib. It is highly suggested that you inform your doctor immediately should you have some allergic reaction to Etoricoxib.

Etoricoxib has the following structural formula:

Chemical structure of etoricoxib


• Molecular formula of etoricoxib is C18H15ClN2O2S
• Chemical IUPAC Name is 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
• Molecular weight is 358.8419 g/mol
Etoricoxib available : 60mg tablets, 90mg tablets, 120mg tablets



Brand name(s): Algix, Arcoxia, Nucoxia, Tauxib


Review published on: 29 April 2008

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