An effective and well known medicament that fights depression is Damilan, a tricyclic antidepressant. It works by inhibiting the serotonin and the noradrenaline reuptake in a patients body and actually increases the level of those natural chemicals so that the level of depression decreases. Typically sold under the names Elavil, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, and Laroxyl, it has sedative effects, so it can also be used to calm people with anxiety or violent depression.
This medicament is most often used by physicians to treat clinical depression and depression in the elderly; however, in some countries it is used to treat chronic migraines, chronic pain, carpal tunnel syndrome and insomnia. A study done in 2003 compared Damilan with a control group of anti depressants, and almost 90% of the subjects had a more favorable response with Damilan.
The most common side effects of this medicament include dry mouth, drowsiness, dizziness, blurred vision, insomnia and weight gain. Because of the drowsiness and dizziness patients experience while taking this medicament, they are discouraged from driving or operating heavy machinery while taking Damilan. The less common side effects include mania, hypotension, psychosis, and hepatic toxicity. If you experience any of these symptoms, seek immediate medical attention.
Patients with a history of seizures, liver diseases, blood diseases, hyperthyroidism, constipation and glaucoma need to advise their physician of these conditions before taking Damilan since they may hinder the medicament. Patients with heart disease need to be particularly careful. This medicament can cause abnormal rhythms in the heart. Patients with manic depression may experience hypermaniac attacks if given Damilan. Physicians may want to adjust the dose or prescribe a different medicament for those patients. The use of Damilan has not been approved for pregnant or breastfeeding women. The medicine is passed through breast milk so mothers should not nurse their children while they are taking the medicament.
Patients should talk with their physician about any and all medicament that they are taking before they use Damilan. Medications like cisapride, monoamine oxidase inhibitors, Marplan, Nardil, Eldepryl, Emsam, Zelapar and Parnate have negative interactions with Damilan. Any medicament you are taking may react negatively with Damilan, even simple medicaments like sleeping pills, antihistamines, diet pills, or herbal vitamins. Make certain that your physician is aware of every medicament you are taking, even those that are non-prescription, to be safe.
Damilan should only be taken as prescribed. The pills are small, white and odorless and come in 10, 25, 50 and 70 mg pills. The dosage for adults and the elderly is usually 25 to 150 mg daily depending on the severity of the condition being treated. It is very important to take the prescribed dosage as too much of the medicament may have negative affects on your mental health.
Damilan has the following structural formula:
• Molecular formula of damilan is C20H23N
• Chemical IUPAC Name is 3-(10,11-dihydro-5H-dibenzo-[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
• Molecular weight is 277.403 g/mol
• Damilan available : 10mg tablets, 25mg tablets, 50mg tablets, 75mg tablets, 100mg tablets, 150mg tablets
Generic name: Amitriptyline
Brand name(s): Adepress, Adepril, Amineurin, Amitid, Amitril, Amitriprolidine, Amitriptylin, Amitryptiline, Amitryptyline, Amytriptiline, Damilen, Damitriptyline, Elanil, Elavil, Endep, Flavyl, Hexathane, Horizon, Lantron, Laroxil, Laroxyl, Lentizol, Pamelor, Proheptadiene, Redomex, Saroten, Sarotex, Seroten, Sylvemid, Triptanol, Triptilin, Triptisol, Tryptanol, Tryptizol
Review published on: 14 January 2010
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