Coroval is a calcium channel blocker that is used mainly for chest pain, also called angina, and hypertension. Calcium makes the arteries contract and become narrow, by blocking the calcium, Coroval helps the blood flow into the heart more smoothly. It also relaxes the muscle in the arteries to help the heart pump blood. Additionally, it reduces blood pressure and increases blood flow to other parts of the body. Chest pain is greatly reduced by the extra supply of blood to the heart. Usually the medicament of choice when treating hypertension and angina, Coroval helps the heart deal with hypertension by increasing the blood flow and relaxing the muscles, so the heart doesn't have to work so hard.
Any prescription or non-prescription medicaments should be discussed with your physician before taking Coroval. Prescription medicaments for HIV, acquired immunodeficiency syndrome, prostate problems, seizures, fungal infections, bacterial infections, or diuretics might be harmful if taken with Coroval. Even herbal medicaments, natural supplements, large amounts of calcium, or vitamins may alter the effectiveness of the medicament. Also, if the patient has had liver or heart disease those organs may be weakened and thus more susceptible to the harmful Coroval effects. Inform your physician immediately if you have ever had any of these diseases. Patients already taking nitroglycerin for angina may continue taking it. Nitroglycerin can be taken with Coroval without any harmful effects.
Some known side effects include: edema, dizziness, headache, upset stomach, rashes, drowsiness, arrhythmia, swelling of the hands and feet, and excessive tiredness. These are negligible side effects that are common with most medicaments. Patients must be careful not to drive after taken Coroval because of the drowsiness that comes with taking the medicament. More serious side effects include severe chest pain, irregular heartbeat and fainting. If any of these occur seek immediate medical attention.
It is not currently known if Coroval is harmful to pregnant women, but if you are pregnant or become pregnant during treatment, inform your physician as a precaution. Only take Coroval if the benefits outweigh the possible danger to the fetus. A warning to mothers: researchers have not yet confirmed if the medicament is passed through breast milk, so as a precaution, nursing mothers should stop breastfeeding while on Coroval.
Coroval is commonly distributed under the names Norvasc and Istin. It is usually available in 5-10 mg pills. Physicians typically prescribe 5mg at the beginning of treatment then gradually increase the dose as they see fit. Coroval usually is in effect for a full 24 hours, so the dose is typically daily. When using this medicament, a low-sodium diet will help the medicament with its course of action.
Coroval has the following structural formula:
• Molecular formula of coroval is C20H25ClN2O5
• Chemical IUPAC Name is methylethyl2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6- methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Molecular weight is 408.876 g/mol
• Coroval available : 2.5mg tablets, 5mg tablets, 10mg tablets
Generic name: Amlodipine
Brand name(s): Amlocard, Amlodipino, Amlodipinum, Amlodis, Amvaz, Lipinox, Lotrel, Norvasc
Review published on: 18 January 2010
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