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  Cardular

 


Cardular

Cardular review by Medicalook.com




Cardular is a brand name for the drug doxazosin mesylate, which is given in tablets to treat two different conditions: Benign Prostatic Hyperplasia, or BHP, and hypertension, or high blood pressure. BPH is a condition found in men in which their prostate is enlarged, but the condition is benign and not due to cancer. The symptoms of BPH include a weak or inconsistent flow of urine, a feeling that you can’t quite empty your bladder fully, the need to urinate frequently, especially during the night, and the feeling that you must urinate urgently. A swollen prostate can lead to other complications, such as urinary tract infections, acute urinary retention (or the inability to urinate), and the need for surgery. Hypertension is when too much blood is being pumped through arteries that are too narrow or blocked. Its symptoms can include headaches, dizzy spells, or nosebleeds, though it often has no symptoms at all. Even without symptoms, it can be threatening to your health and should be treated with a medication such as Cardular. Cardular can be used alone or along with diuretics, beta-blockers, calcium channel blockers, or angiotensin-converting enzyme inhibitors.

The most common side effects of Cardular are dizziness and headaches, which occur in less than 20% of patients. Other side effects are very rare, but can include fatigue, malaise, back pain, chest pain, low blood pressure, palpitations, diarrhea or constipation, abdominal pain, heartburn, nausea, swelling, dry mouth, sleepiness or insomnia, difficulty breathing, vision disturbances, impotence, anxiety, irregular heartbeat, rash or hives, wobbliness, flushing, muscle cramps, eye pain, numbness or tingling, nervousness, depression, ringing in the ears, flatulence, vomiting, runny nose, nosebleeds, or urinating frequently. Other rare side effects include hair loss, loss of appetite or increased appetite, earache, sinus infection, coughing, tremor, migraine, fever, breast pain or swelling, or allergic reaction.

Those taking Cardular should begin with a very small dose, just 1 mg. The first dosage can cause serious effects such as low blood pressure and dizziness. Once the body has adjusted to the lower dosage, it can gradually be increased to a more appropriate dosage for your condition and body size. You should avoid driving a car or other dangerous activities until you are completely sure that you will not have an episode of dizziness or even loss of consciousness from low blood pressure.

Cardular is in Pregnancy Category C, which means that it is not known whether it is harmful to pregnant women or their developing fetuses. Animal studies do not indicate that Cardular harms a fetus until the animals are administered extremely high dosages, but because animal studies do not always translate to human results, it is recommended that you only take Cardular during pregnancy if it is absolutely necessary. It is not known whether Cardular passes into breast milk, so you should consult with your doctor if you are nursing or planning to nurse a child. Cardular has not been evaluated for use in pediatric patients, so it is not recommended for children.

Cardular has the following structural formula:

Chemical structure of cardular


• Molecular formula of cardular is C23H25N5O5
• Chemical IUPAC Name is [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-(2,5- dioxabicyclo[4.4.0]deca-6,8,10-trien-4-yl)methanone
• Molecular weight is 451.475 g/mol
Cardular available : 1mg tablets, 2mg tablets, 4mg tablets, 8mg tablets



Generic name: Doxazosin

Brand name(s): Alfadil, Cardenalin, Cardura, Carduran, Diblocin, Normothen, Supressin


Review published on: 23 March 2008

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