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Bimatoprost review
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Bimatoprost is a prostaglandin-like medication often used in eye drops for glaucoma treatment. It acts by reducing interocular pressure, thereby improving vision and averting permanent damage to eyesight. Bimatoprost does this by increasing the outward flow of fluids found within the eye – reducing pressure on the optic nerve. It is available under the brand name Lumigan, which comes in a 0.03% solution.
Bimatoprost has also been marketed as a cosmetic eyelash lengthener, under the brand name Latisse. However, a more curious potential use being explored by people for this drug is to lessen ocular fat. Unilateral fat loss in both eyes has been observed, even when it is only applied in a single eye. The effect however seems reversible.
Bimatoprost, particularly Lumigan, is prescribed to patients suffering from ocular hypertension and open angle glaucoma. Latisse on the other hand, may be used to treat hypotrichosis aside from its cosmetic use. Bimatoprost is particularly administered for patients who find that they cannot use other eye medication for their condition or find that they eye medication previously used was ineffective.
Bimatoprost is usually administered once a day (usually in the evening) to the affected eye or eyes. It is recommended to use it the same time each day to prevent missing doses. Always follow the prescription and listen to the special instructions given by your doctor.
Bimatoprost cannot cure glaucoma but only manages the interocular pressure. Continue applying bimatoprost even if your vision has already improved. Do not discontinue treatment without your doctor’s knowledge.
To apply the bimatoprost eye drops, first make sure that your hands are clean. You’re your head back and lightly pull down your lower eyelid to create a pocket. Make sure the dropper nozzle does not touch your eye as you prepare to place the prescribed number of drops into the pocket. Do not place the drops directly onto the eye surface as this may cause irritation. Close the affected eye for 2 to 3 minutes for the medication to work. Do not blink nor rub your eyes.
The use of bimatoprost eye drops may cause undesired side effects. This may include itching and burning of the eyes, dryness, tearing and other symptoms of eye irritation. See your doctor if these effects persist.
More sensitive effects include light sensitivity, presence of pink eye or excess redness or swelling of the affected eyelid. Seek immediate medical attention if these symptoms occur.
Discoloration of the eye to brown has also been observed, as well as the darkening of the skin around the eye. As a side effect, longer and darker eyelashes may result from bimatoprost use. While these changes can occur very gradually over time, they can also be permanent changes in the body.
If you use any other topical eye medication, apply it 5 minutes before or after bimatoprost application. Remove contact lenses when administering bimatoprost eye drops as the soft lenses may absorb the medication. Replace the lenses 15 minutes after the last application of bimatoprost.
Inform your doctor if you have inflammation or any other condition of the eye and if you have or have ever had liver or kidney disease – Bimatoprost may interact with these conditions. Avoid breastfeeding while on bimatoprost and avoid pregnancy for the mean time.
Bimatoprost has the following structural formula:
• Molecular formula of bimatoprost is C25H37NO4
• Chemical IUPAC Name is 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide
• Molecular weight is 415.566 g/mol
Brand name(s): Lumigan
Review published on: 16 June 2009
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