Benazepril falls under the angiotensin-covering enzyme (ACE) inhibitor type of medicines. This means that it regulates a chemical in our bodies that tightens blood vessels, letting blood flow more smoothly and more easily. Beyond this, it can even help weak hearts pump blood more efficiently. These functions are what make Benazepril a potent prescription drug for high blood pressure. Its most popular brand is Lotensin.
It is extremely important to note that Benazepril is very dangerous for fetuses. It can cause serious injury, malformation, and even death to unborn babies. Women who are beyond their third month of pregnancy should never take Benazepril. A woman who becomes pregnant while taking the drug should immediately inform her physician.
People who have allergies to ACE inhibitors should not take this drug. Those who also have high levels of potassium in their bodies or are currently taking potassium supplements should take this with caution, as Benazepril combined with these can lead to near-fatal levels of potassium. There are also several other medicines that may interact with Benazepril and have severe results, such as Lithium, diuretics, and diabetes medication. Inform your doctor of such medication beforehand to ensure your safety.
Children above the age of 6 may use Benazepril upon the prescription of a doctor.
An orally ingested drug, Benazepril may be taken even on an empty stomach. It is usually taken one or two times a day. If your physician prescribes otherwise, however, you should follow what he or she gives you strictly. If a dosage is missed, take it as soon as you remember, but do not take more than the prescribed amount at one time to compensate. In case of accidental overdosage, immediately seek medical attention for poisoning.
Avoid ingesting alcohol if you are taking Benazepril, as it may emphasize its side effects. Make sure to inform your doctor beforehand if you are combining Benazepril with other types of medication to be certain that it will not be detrimental to your health. Do not perform any potentially dangerous tasks such as driving until you are sure of Benazepril’s effects on you. On occasion, the drug has been found to cause extreme sleepiness in patients.
As previously mentioned, avoid high-potassium foods. Your physician may also prescribe low salt and low sodium diets. Follow the diet closely.
Benazepril is a generally stable drug. Studies have shown that its side effects are just minimal and usually pass quickly. Among these effects are headaches, drowsiness, persistent dry cough, and slight nausea. Unless these are severe, there is no need to worry. Do inform your doctor right away, however, if you experience fever, irregular heartbeat, hoarseness, swelling, fainting, and jaundice. These might be indicative of graver, more serious effects.
Have regular blood tests to make sure there are no adverse long-term effects. Also inform him/her if you expect to have medical or dental surgery.
Benazepril must be stored at room temperature at a dry location in a tightly sealed container.
Benazepril has the following structural formula:
• Molecular formula of benazepril is C24H28N2O5
• Chemical IUPAC Name is 2-[4-(1-ethoxycarbonyl-3-phenyl-propyl)amino-5-oxo- 6-azabicyclo[5.4.0]undeca-7,9,11-trien-6-yl]acetic acid
• Molecular weight is 424.49 g/mol
• Benazepril available : 5mg tablets, 10mg tablets, 20mg tablets, 40mg tablets
Brand name(s): Benazeprilum, Briem, Cibacen, Cibacene, Lotensin, Lotrel
Review published on: 08 March 2008
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