Bactrim is a combination antibiotic which is generically prescribed as sulfamethoxazole and trimethoprim. Bactrim is also commonly prescribed as Bethaprim, Cotrim, Septa, Sulfatrim, and Uroplus, each with a pediatric version as well. Bactrim is typically used in the treatment of bacterial infections such as bronchitis, urinary tract infections, traveler’s diarrhea, ear infections, or Pneumocystis carinii pneumonia.
Bactrim is not appropriate for everyone and it is vital that the prescribing physician understand a patient’s medical history prior to prescribing this medication. Bactrim is not appropriate for patients with liver disease, kidney disease, or glucose-6 phosphate deficiency. Patients with these diseases or conditions in their medical history may not be able to tolerate Bactrim or may require special monitoring while undergoing drug therapy with this medication, depending on the condition and its severity.
The American Food and Drug Administration rated Bactrim as a category C pregnancy risk, which means that it has yet to be determined what impact Bactrim may have on a developing fetus. Bactrim does deplete the body of folic acid, and the lack of folic acid in a pregnant woman’s body may cause birth defects. Bactrim passes through the mother’s breast milk and is likely to affect a nursing baby. Women who are pregnant must consider whether the benefits outweigh the risks before taking Bactrim and women who are nursing should avoid Bactrim altogether.
There is a risk of side effects associated with the use of Bactrim. Serious side effects and allergic reaction will require medical assessment and intervention. Allergic reactions include symptoms like facial swelling, difficulty breathing, and hives. Other serious side effects may include symptoms like yellowing of the skin or whites of the eyes, easy bruising, and easy bleeding. A patient experiencing these symptoms may be having a detrimental organ reaction.
Of course less serious side effects are much more common and are likely to include symptoms such as weakness, dizziness, fatigue, nausea, vomiting, diarrhea, loss of interest in food, headaches, and an increased sensitivity to the sun. If a patient develops these or other side effects, typically they simply require alerting the prescribing physician.
Bactrim should be taken only as prescribed. Patients who take a double dose of this medication or take doses too close together are risking an overdose. If a dose of Bactrim is missed, the dose should be taken when remembered unless it is close to the next dose in which case the missed dose can be skipped. An overdose requires immediate emergency medical assessment. An overdose of Bactrim is likely to present with symptoms which include nausea, vomiting, diarrhea, headaches, loss of appetite, jaundice, difficulty in producing urine, bloody urine, coma, and death.
Bactrim is known to have interactions with other medications. Patients taking Bactrim or any other medication should always consult with the prescribing physician before adding any new medications, over the counter or prescription, to their daily regimen. This includes herbal remedies and vitamin supplements. Medications with known interactions to Bactrim include blood thinners, diabetes medication, phenytoin, and additional antibiotics.
Bactrim needs to be taken for as long as it has been prescribed, as stopping too early may invite the infection to return stronger and more difficult to treat. Patients should not stop taking this medication even if their symptoms clear up.
Bactrim has the following structural formula:
• Molecular formula of bactrim is C10H11N3O3S
• Chemical IUPAC Name is 4-amino-N-(5-methyloxazol-3-yl)-benzenesulfonamide
• Molecular weight is 253.279 g/mol
• Bactrim available : 400-80mg Tablets
Generic name: Trimethoprim
Brand name(s): Abacin, Abaprim, Alprim, Apo-Sulfatrim, Bactin, Bactramin, Bactrim Ds, Baktar, Chemotrim, Co-trimoxazole, Comox, Cotrim, Drylin, Eusaprim, Fectrim, Gantaprim, Gantrim, Idotrim, Imexim, Instalac, Ipral, Kepinol, Laratrim, Lidaprim, Linaris, Methoprim, Microtrim, Monoprim, Monotrim, Monotrimin, Nopil, Oraprim, Priloprim, Primosept, Primsol, Proloprim, Septra, Septra Ds, Septrin, Sigaprim, Sulfamethoprim, Sulfatrim, Sulfatrim-Ds, Sulfatrim-Ss, Sulfotrim, Sulmeprim, Sulprim, Sumetrolim, Supracombin, Suprim, Syraprim, Teleprim, Thiocuran, Tiempe, Trigonyl, Trimanyl, Trimesulf, Trimethioprim, Trimethopriom, Trimetoprim, Trimexazole, Trimogal, Trimopan, Trimpex, Triprim, Unitrim, Uretrim, Uro-Septra, Uroplus, Uroplus Ds, Uroplus Ss, Veltrim, Wellcoprim
Review published on: 21 May 2007
Your Bactrim review
| .: Add date: 2007-08-10 13:28:04 |
.: Score: 7 |
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You forget to mention the underskin rash that is possible to get due to the drug. Which I unfortunately experienced as a side effect, it fortunately has not turned into hives or anything more serious... at least not yet.
Added by Tess
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| .: Add date: 2007-08-13 11:05:26 |
.: Score: 3 |
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I have just broken out in a bright red rash and am extremely itchy and a little dirorientated. First time I have ever had a reaction to any medication in 47 years.
Added by Sally
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| .: Add date: 2007-08-14 15:45:54 |
.: Score: 1 |
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I broken out in a rash on the 5th day. From day one I had fatique and flat-out weakness all over. I will never it again
Added by jordan
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| .: Add date: 2007-09-07 20:03:53 |
.: Score: 1 |
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I broke out in hives- and now 3 weeks later I have a new rash that doctors can't figure out...I wonder if it is still from the reaction to bactrim!
Added by brandi
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| .: Add date: 2007-09-23 11:10:37 |
.: Score: 10 |
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great presentation, I am on Bactrim now for a uti resistant to Cipro
Added by tschop
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| .: Add date: 2008-12-31 08:48:19 |
.: Score: 1 |
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I have a non-bacterial inflamation of the prostate. Bactrim was prescribed by my irologist when after my urine was found to be normal. I became sererely constipated after taking all the medicine. I still have urination problems. Nobody seems to be able to offer a solution except to prescribe chemicals. Bactrim kills all the good a bad germs and then it kills you afterwards. Beware!
Added by Jim
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| .: Add date: 2009-03-02 18:28:21 |
.: Score: 10 |
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Also I have hives, and some hair loss. My face is a mess. This medication should be looked into further.
Added by vet
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| .: Add date: 2009-06-13 02:45:02 |
.: Score: 1 |
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I was on this for one day and went to bed the next day I woke up with a horrible rash in a very sensitive area and it was very painful,I would never take it again
Added by Athena
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| .: Add date: 2009-07-27 18:02:31 |
.: Score: 1 |
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I cannot understand how this drug was approved by the FDA. I also took this drug and had many reactions, all of which I was told were not allergic reactions to the medicine. One doctor finally agreed it had to be the Bactrim based on all the things going wrong. Severe chill and vomiting; underskin rash with skin discoloration; severe neck stiffness, massive headaches, loss of muscle control in legs. When finally taken off drug, three to four days later all symptoms vanished. Two weeks later developed intestinal bleeding and wonder if that was also caused by this drug. Three months later doctor prescribed Bactrim again for a uti saying that I never really had a reaction. Within 24 hours of taking first pill I began to develop some of the same symptoms again. Will never take this again. Have told my pharmasist I never want to take another drug of this class and to please make a not on my record.
Added by Debbie
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| .: Add date: 2009-09-28 03:40:51 |
.: Score: 1 |
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I wouldn't give this drug to my worst enemy. Should be pulled from mark.Rash, face swelling , kidney stones, plus others doctor said I could have died only took for 2 days.
Added by Pat
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| .: Add date: 2009-10-10 04:39:21 |
.: Score: 1 |
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Started taking Bactrim 8 days ago for UTI. On the 6th day noticed a small rash but it quickly covered my whole body and was very itcy. I took some Benedryl and used cortisone cream because the tops of my feet felt like they were burning. A day later, (I was still taking the Bactrim, but also taking Benedryl) I had severe pain in my joints and it hurt to stand or walk. Got home from my business trip and visited my physician who put me on predinisone. Just because I was going to see the Dr. I didn't take the last pill - I figured I could take it after I saw him. I felt better almost immediately, but not 100%. He told me if it doesn't get better to go to the ER becuase it could have developed into SJS disease. I will NEVER use this again. I have never in my life had a drug reaction.
Added by saw
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| .: Add date: 2009-10-20 14:39:57 |
.: Score: 10 |
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i took bactrim for three days and wow i have had severe itching on both arms then both legs then my crotch i haven't taken any for 10 days now but still have hives and itching and redness' i had a shot yesterday now 12 days of steriod' i am a mess
Added by karen
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| .: Add date: 2009-10-30 03:36:28 |
.: Score: 2 |
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After 4 days, I have horribly dry skin, can't get enough to drink, having some trouble peeing, and I have the worst yeast infection I've ever had in my life. It is actually painful to sit down!
Added by mary
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| .: Add date: 2009-11-07 16:18:57 |
.: Score: 7 |
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I was prescribed bactrim and another antibiotic for cellulitis and 6 days later I developed a small rash, the next day the rash covered my neck and upper portion of my chest. On the 8th day, my entire neck, most of my arms, portions of my torso, back, thighs and affected area where cellulits is was covered in hives. Went to ER and got steriod shot THEN heard of the bad side effects of this drug. I am in a long haul of healing from my cellulitis and now the allergic reaction, I would like to thank :( the makers of this medicine for making the effects worse than the condition I had.
Added by Annette
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