Atrovent is a brand name for the generic medication ipratropium bromide. It is used to treat difficulty breathing due to chronic obstructive pulmonary disease (COPD), which can include chronic bronchitis and emphysema. It is also used to prevent painful bronchospasms. Atrovent comes in an inhalation aerosol. This inhaler needs to be primed by spraying it twice into the air the first time you use it, or if you have not used it in three days or more, in order to clear out clogs in the mechanism that might affect the dosage of the aerosol. Most patients start their Atrovent with two inhalations taken four times a day. In some cases, Atrovent is prescribed in conjunction with other medications to fully treat the patient’s condition.
Atrovent is generally well tolerated, and patients generally suffer few side effects from it. Some common minor side effects can include headache, dizziness, dry mouth, cough, hoarse voice, blurred vision, nausea or upset stomach. Other rare but serious side effects can include a worsening of glaucoma, eye pain, fatigue, insomnia, low blood pressure, inability to urinate, dilation of the pupils, flushing, hair loss, irregular or rapid heart beat, or constipation. People very seldom experience an allergic reaction to Atrovent, but if you do, it will appear as a rash or hives, swelling of the throat, face, tongue or lips, and difficulty breathing. It is very important not to spray Atrovent into your eyes, as this can worsen certain eye conditions and cause you pain and irritation.
Some people should use extreme caution when considering treatment with Atrovent. If you are allergic to soybeans or peanuts, or other substances containing soya lecithin, or of you are sensitive to atropine, you should not take Atrovent. You should tell your doctor if you have narrow-angle glaucoma, prostate or urinary problems, a history of heart disease, seizures, a thyroid disorder, diabetes, low potassium levels, kidney disease, liver disease, or if you are pregnant. People in those groups may have their doses adjusted or may require a different treatment. Your doctor may require you to have regular tests to make sure that Atrovent is working as it should be.
Atrovent is in pregnancy category B, which means that studies have shown no indication that inhaling Atrovent can cause harm to a developing fetus or a pregnant woman. Even so, if you are pregnant, you should avoid taking Atrovent unless it is clearly necessary. The same is true for breast feeding; it is not known whether Atrovent passes into breast milk, so talk to your doctor and use caution if you are nursing a baby or plan to do so. Atrovent has not been studied in children, so its safety and effectiveness for them are not known. For that reason it is not recommended for use in children under twelve years of age. Atrovent is as safe and effective in patients over age sixty-five as it is in patients younger than that.
Atrovent has the following structural formula:
• Molecular formula of atrovent is C20H30NO3
• Chemical IUPAC Name is [8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]oct-3-yl]3-hydroxy-2-phenyl-propanoate
• Molecular weight is 332.457 g/mol
• Atrovent available : 0.06% solution 15 ml nasal spray, 0.03% solution 30 ml nasal spray
Generic name: Ipratropium
Brand name(s): Aerovent, Apo-Ipravent, Apovent, Atronase, Bitrop, Disne-Asmol, Ipravent, Ipvent, Narilet, Rhinotrop, Rhinovent, Rinatec, Rinoberen, Rinovagos, Vagos
Review published on: 09 January 2008
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